The Most Astounding Fact — Neil DeGrasse Tyson
When I first understood this (probably thanks to Isaac Asimov’s books or Carl Sagan’s Cosmos) I thought it was amazing. This presentation is beautiful:
[youtube=http://www.youtube.com/watch?v=9D05ej8u-gU&w=640&h=360]
UPDATE 2012-03-16: And here is the 10 questions which inspired it (with an astounding tribute to Isaac Newton):
[youtube=http://www.youtube.com/watch?v=wiOwqDmacJo&w=420&h=315]